Payne's mother Emma opposed university education initially. She feared Cecilia would become unmarriageable. But Cecilia won scholarship to Cambridge. Her mother relented. At Newnham College, Cecilia studied natural sciences. She attended Arthur Eddington's lecture on 1919 solar eclipse. Einstein's relativity was confirmed. Cecilia decided astronomy was her calling.
Cambridge refused to grant degrees to women. Payne could attend lectures and take exams. But university would not award diploma. Career prospects in Britain were nonexistent. Women could not hold faculty positions. Eddington recognized her talent. He recommended her to Harlow Shapley at Harvard.
Shapley offered fellowship in 1923. Payne sailed to America alone at age 23. She never returned to live in Britain. At Harvard, she joined team of "computers" - women who analyzed astronomical data. These women received low pay and no recognition. But they did groundbreaking work. Payne seized opportunity. She pursued PhD while analyzing spectra. Her thesis revolutionized astrophysics.